Glucomannan . This natural fiber product comes from the konjac plant. While diet supplements that contain glucomannan (such as Lipozine) say it is effective for weight loss, a study published in the well-respected Journal of Obesity found that the herbal supplement did not promote weight loss. The National Institutes of Health also states that only limited evidence supports its effectiveness.
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Natural Medicines says that CLA is "possibly effective" for weight loss. Some researchers warn that long-term use, especially if you're obese , may raise insulin resistance , which makes it more
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